I like my doctor, Lou. The guy knows what he's doing, cares about his patients and shows it, and keeps up with the latest stuff. Today I had a routine physical exam, part of which is going through the results of recent lab tests, and I got an earful from the good doctor about a new way of looking at blood chemistry. I hadn't seen Lou this animated about something in a while, and so I knew I should listen up.
From time immemorial we've all heard that we need to keep an eye on our cholesterol, and a couple of decades ago we refined that down to LDL, the "bad" one, and HDL, the "good" one. If I've got this right, the numbers we've always gotten in our blood tests have measured the volumes of those substances in the blood.
But now it appears that within the realm of LDL, they're figuring out that the number and size of the particles that carry the cholesterol are what's important. As I understand it, size matters, in that big LDL particles aren't as damaging as small ones. The big ones can't get through to start messing up your arteries, whereas the little ones can. And the more LDL particles of any size there are, the worse off the patient is. Apparently, the greater the number of vehicles careening around in there, the greater the risk that one or more are going to hit something. Therefore, in addition to watching LDL and HDL in the bloodstream, it's also smart to keep an eye on one's "LDL particle number" and "small LDL particle number." You want both those numbers -- the numbers of "bad" particles floating around -- to be low. You may have a low volume of LDL, but if there are too many particles, you could still be a candidate for trouble. And on the size of the LDL particles, the bigger the better.
I hope I got that right. I probably shouldn't prattle on so much about something I don't really understand, but maybe this will get somebody who's due for a physical in to see his or her physician soon. Who knows? Maybe your "bad" cholesterol situation isn't as bad as you thought -- or maybe where you thought you were in the clear, it ain't necessarily so. Meanwhile, on my end, it's nice to watch something new while I'm watching myself get older.
Comments (6)
The next time you talk with Lou the Dr, ask him how much he knows about inflammation in the vascular system, how it affects coronary artery disease, and why lots of people are much more concerned about inflammation issues than cholesterol. In countries that consume significantly more seafood, especially of the fatty kind, coronary disease is way lower than in the US. Japan is about one of the lowest with Inuit populations that survive on large doses of salmon and other fatty fish (or mammals). The cholesterol debate is bizarre but seeing statistics that compare increased seafood consumption with lower mortality rates speaks for itself.
The weird part of this is that FDA suggests that we consume 2-6oz portions of fish or seafood per week. Our average consumption in the US is about 16 lbs per year. Calculating the 2-6 oz portions over the course of a year would yield about 42 pounds AVERAGE. The issue is that there isn't enough fish to harvest to make up that amount. So I guess only the ones who get the message will survive.
Your Doctor was right on!
I was fortunate to attend a standing-room only talk by Dr. John McDougall a few weeks ago. He is a leading proponent of a plant-based, no fat diet. The dangers of the tiny plaques inside arteries are the real dangers - not the large "old" LDL particles. Where do these plaques come from? Our western diet - animal-based high fat diets.
Here is a link to a "conversation" that Dr. McDougall had with Tim Russert after his death. It was controversial, but contained some great information about LDL and heart disease. http://www.drmcdougall.com/misc/2008nl/jun/russert.htm
I have been a vegan on a no fat (that's right - no olive oil!) for a few months. I've been a vegetarian for a number of years, but feel so much better on my new way of eating. I've lost weight and have much more energy.
There are several physicians and researchers out there who are taking on big pharma, the meat and dairy industries and the processed food companies to try to get out real information on health and nutrition. Among them are Dr. John McDougall, Dr. Caldwell B. Esselstyn (author of " Prevent and Reverse Heart Disease" and T. Colin Campbell, PhD., author of The China Study".
I hope everyone reads the article in the Sunday NY Times (on the website) about the tainted hamburgers - disgusting!!
It's nice to think that your doctor is on top of the health news that affects you. But there are other possibilities for explaining what he is going on.
If you are not a health professional, it is comforting to believe that your medical practitioner always acts on a sound scientific basis. But unfortunately, there are fads among health practitioners just as with every other kind of human endeavor.
Consider cholesterol. First we were told that total cholesterol was the important number to look at. Then different schools argued that either hdl, ldl, or triglycerides were individually most important. Then there are whole schools that talk about the ratio of one or more of these elements to the others as the most important consideration. Now the latest hype is that you should look at the size of your ldl particles. You can be sure that within the next few years there will be still another "breakthrough" explanation of how some aspect of cholesterol affects heart disease.
Are we seeing real progress here or just the occurrence of fads in the health and medical professions? Is there any noticeable downward effect of the incidence of heart disease?
There's a great book called "The Last Well Person: How to stay healthy despite the health care system" by a Harvard doc who teaches at a med school in North Carolina, Nortin Hadler. It's a really, really powerful book, with a big chapter on statins and heart disease in general, and other chapters on evaluating health claims, benefits, etc.
Couple that with Shannon Brownlee's book "Overtreated: How too much health care is making us sicker and poorer" and you really get a different perspective on things. Where we need a lot more health care is in the low-profit end of things (primary care, preventive care); what we get are fabulously expensive things like systems to measure LDL particle size for white guys with lots of insurance.
Charamba, Douro 2008
Horse Heaven Hills, Cabernet 2010
Lorelle, Horse Heaven Hills Pinot Grigio 2011
Avignonesi, Montepulciano 2004
Lorelle, Willamette Valley Pinot Noir 2011
Villa Antinori, Toscana 2007
Mercedes Eguren, Cabernet Sauvignon 2009
Lorelle, Columbia Valley Cabernet 2011
Purple Moon, Merlot 2011
Purple Moon, Chardonnnay 2011
Abacela, Vintner's Blend No. 12
Opula Red Blend 2010
Liberte, Pinot Noir 2010
Chateau Ste. Michelle, Indian Wells Red Blend 2010
Woodbridge, Chardonnay 2011
King Estate, Pinot Noir 2011
Famille Perrin, Cotes du Rhone Villages 2010
Columbia Crest, Les Chevaux Red 2010
14 Hands, Hot to Trot White Blend
Familia Bianchi, Malbec 2009
Terrapin Cellars, Pinot Gris 2011
Columbia Crest, Walter Clore Private Reserve 2009
Campo Viejo, Rioja, Termpranillo 2010
Ravenswood, Cabernet Sauvignon 2009
Quinta das Amoras, Vinho Tinto 2010
Waterbrook, Reserve Merlot 2009
Lorelle, Horse Heaven Hills, Pinot Grigio 2011
Tarantas, Rose
Chateau Lajarre, Bordeaux 2009
La Vielle Ferme, Rose 2011
Benvolio, Pinot Grigio 2011
Nobilo Icon, Pinot Noir 2009
Lello, Douro Tinto 2009
Quinson Fils, Cotes de Provence Rose 2011
Anindor, Pinot Gris 2010
Buenas Ondas, Syrah Rose 2010
Les Fiefs d'Anglars, Malbec 2009
14 Hands, Pinot Gris 2011
Conundrum 2012
Condes de Albarei, Albariño 2011
Columbia Crest, Walter Clore Private Reserve 2007
Penelope Sanchez, Garnacha Syrah 2010
Canoe Ridge, Merlot 2007
Atalaya do Mar, Godello 2010
Vega Montan, Mencia
Benvolio, Pinot Grigio
Nobilo Icon, Pinot Noir, Marlborough 2009
Portuga, Rose 2011
Revelation, Chardonnay, Pays d'Oc 2010
Beaulieu, Cabernet, Rutherford 2005
Monte Alto, Tinto Reserva 2005
Chateau Ste. Michelle, Cabernet, Indian Wells 2009
Espiral, Vinho Rose
Vin-Koru, Pinot Gris 2011
14 Hands, Hot to Trot Red 2009
Rodney Strong, Cabernet, Sonoma 2009
Abacela, Vintner's Blend #11
Portuga, White 2010
La Bourgeoisie, Red 2009
Januik, Red 2009
Three Rivers, River's Red 2008
Kirkland, Alexander Valley Merlot 2008
Muga, Rioja Rose 2010
Quinta das Amoras, Vinho Tinto 2009
Mauro Molino, Barbera d'Alba 2009
Garda Chiaretto Rose
Columbia Crest, Two Vines Vineyard 10 White
Chateau Ste. Michelle, Pinot Gris, Columbia Valley 2009
L'Hortus, Rose de Saignee 2010
Maculan, Pino & Toi 2008
McKinley Springs, Bombing Range Red 2008
Trader Joe's Pinot Gris 2009
Montes Alpha, Cabernet 2007
Gran Sasso, Sangiovese, Terre di Chieti 2009
Garda, Classico Chiaretto Rose
Beaulieu, Cabernet, Rutherford 1999
Picos del Montgo, Tempranillo 2008
Chateau de Montmirail, Vacqueyras 2008
La Granja 360, Syrah 2009
Montgras, Carmenere Reserva 2009
Lange, Pinot Gris 2009
Columbia Crest, Horse Heaven Hills Cabernet 2008
Kirkland, Pinot Grigio 2010
Trader Joe's Coastal Syrah 2009
Columbia Crest, Horse Heaven Hills Merlot 2008
Trader Joe's Coastal Chardonnay 2009
Vieux Papes Red
Domaine de l'Aujardiere, Chardonnay 2009
Santa Rita, Cabernet, Medalla Real 2007
Penfold's, Koonunga Hill Shiraz Cabernet 2008
Guild, Red, Lot #02 2008
Dievole, Dievolino Sangiovese 2008
Laforet, Burgogne Chardonnay 2009
Columbia Winery, Merlot 2007
Bonterra, Cabernet 2008
Elk Cove, Pinot Gris 2009
Maquis Lien 2006
Scott Paul, Pinot Noir, Le Paulee 2007
The Occasional Book
Neil Young - Waging Heavy Peace
Mark Bego - Aretha Franklin, the Queen of Soul (2012 ed.)
Jenny Lawson - Let's Pretend This Never Happened
J.D. Salinger - Franny and Zooey
Charles Dickens - A Christmas Carol
Timothy Egan - The Big Burn
Deborah Eisenberg - Transactions in a Foreign Currency
Kurt Vonnegut Jr. - Slaughterhouse Five
Kathryn Lance - Pandora's Genes
Cheryl Strayed - Wild
Fyodor Dostoyevsky - The Brothers Karamazov
Jack London - The House of Pride, and Other Tales of Hawaii
Jack Walker - The Extraordinary Rendition of Vincent Dellamaria
Colum McCann - Let the Great World Spin
Niccolò Machiavelli - The Prince
Harper Lee - To Kill a Mockingbird
Emma McLaughlin & Nicola Kraus - The Nanny Diaries
Brian Selznick - The Invention of Hugo Cabret
Sharon Creech - Walk Two Moons
Keith Richards - Life
F. Sionil Jose - Dusk
Natalie Babbitt - Tuck Everlasting
Justin Halpern - S#*t My Dad Says
Mark Herrmann - The Curmudgeon's Guide to Practicing Law
Barry Glassner - The Gospel of Food
Phil Stanford - The Peyton-Allan Files
Jesse Katz - The Opposite Field
Evelyn Waugh - Brideshead Revisited
J.K. Rowling - Harry Potter and the Sorcerer's Stone
David Sedaris - Holidays on Ice
Donald Miller - A Million Miles in a Thousand Years
Mitch Albom - Have a Little Faith
C.S. Lewis - The Magician's Nephew
F. Scott Fitzgerald - The Great Gatsby
William Shakespeare - A Midsummer Night's Dream
Ivan Doig - Bucking the Sun
Penda Diakité - I Lost My Tooth in Africa
Grace Lin - The Year of the Rat
Oscar Hijuelos - Mr. Ives' Christmas
Madeline L'Engle - A Wrinkle in Time
Steven Hart - The Last Three Miles
David Sedaris - Me Talk Pretty One Day
Karen Armstrong - The Spiral Staircase
Charles Larson - The Portland Murders
Adrian Wojnarowski - The Miracle of St. Anthony
William H. Colby - Long Goodbye
Steven D. Stark - Meet the Beatles
Phil Stanford - Portland Confidential
Rick Moody - Garden State
Jonathan Schwartz - All in Good Time
David Sedaris - Dress Your Family in Corduroy and Denim
Anthony Holden - Big Deal
Robert J. Spitzer - The Spirit of Leadership
James McManus - Positively Fifth Street
Jeff Noon - Vurt
Road Work
Miles run year to date: 21
At this date last year: 52
Total run in 2012: 129
In 2011: 113
In 2010: 125
In 2009: 67
In 2008: 28
In 2007: 113
In 2006: 100
In 2005: 149
In 2004: 204
In 2003: 269
Comments (6)
The next time you talk with Lou the Dr, ask him how much he knows about inflammation in the vascular system, how it affects coronary artery disease, and why lots of people are much more concerned about inflammation issues than cholesterol. In countries that consume significantly more seafood, especially of the fatty kind, coronary disease is way lower than in the US. Japan is about one of the lowest with Inuit populations that survive on large doses of salmon and other fatty fish (or mammals). The cholesterol debate is bizarre but seeing statistics that compare increased seafood consumption with lower mortality rates speaks for itself.
The weird part of this is that FDA suggests that we consume 2-6oz portions of fish or seafood per week. Our average consumption in the US is about 16 lbs per year. Calculating the 2-6 oz portions over the course of a year would yield about 42 pounds AVERAGE. The issue is that there isn't enough fish to harvest to make up that amount. So I guess only the ones who get the message will survive.
Posted by Gef Flimlin | October 6, 2009 5:50 AM
homosystines...ask about that!
And all this drivel from big pharma about all the meds for high cholesterol could be just totally bogus.
Posted by portland native | October 6, 2009 9:25 AM
Your Doctor was right on!
I was fortunate to attend a standing-room only talk by Dr. John McDougall a few weeks ago. He is a leading proponent of a plant-based, no fat diet. The dangers of the tiny plaques inside arteries are the real dangers - not the large "old" LDL particles. Where do these plaques come from? Our western diet - animal-based high fat diets.
Here is a link to a "conversation" that Dr. McDougall had with Tim Russert after his death. It was controversial, but contained some great information about LDL and heart disease.
http://www.drmcdougall.com/misc/2008nl/jun/russert.htm
I have been a vegan on a no fat (that's right - no olive oil!) for a few months. I've been a vegetarian for a number of years, but feel so much better on my new way of eating. I've lost weight and have much more energy.
There are several physicians and researchers out there who are taking on big pharma, the meat and dairy industries and the processed food companies to try to get out real information on health and nutrition. Among them are Dr. John McDougall, Dr. Caldwell B. Esselstyn (author of " Prevent and Reverse Heart Disease" and T. Colin Campbell, PhD., author of The China Study".
I hope everyone reads the article in the Sunday NY Times (on the website) about the tainted hamburgers - disgusting!!
Posted by Mary | October 6, 2009 11:05 AM
It's nice to think that your doctor is on top of the health news that affects you. But there are other possibilities for explaining what he is going on.
If you are not a health professional, it is comforting to believe that your medical practitioner always acts on a sound scientific basis. But unfortunately, there are fads among health practitioners just as with every other kind of human endeavor.
Consider cholesterol. First we were told that total cholesterol was the important number to look at. Then different schools argued that either hdl, ldl, or triglycerides were individually most important. Then there are whole schools that talk about the ratio of one or more of these elements to the others as the most important consideration. Now the latest hype is that you should look at the size of your ldl particles. You can be sure that within the next few years there will be still another "breakthrough" explanation of how some aspect of cholesterol affects heart disease.
Are we seeing real progress here or just the occurrence of fads in the health and medical professions? Is there any noticeable downward effect of the incidence of heart disease?
Posted by davidg | October 6, 2009 11:41 AM
There's a great book called "The Last Well Person: How to stay healthy despite the health care system" by a Harvard doc who teaches at a med school in North Carolina, Nortin Hadler. It's a really, really powerful book, with a big chapter on statins and heart disease in general, and other chapters on evaluating health claims, benefits, etc.
Couple that with Shannon Brownlee's book "Overtreated: How too much health care is making us sicker and poorer" and you really get a different perspective on things. Where we need a lot more health care is in the low-profit end of things (primary care, preventive care); what we get are fabulously expensive things like systems to measure LDL particle size for white guys with lots of insurance.
Posted by George Anonymuncule Seldes | October 6, 2009 12:04 PM
I have to second Mary's post about Dr. McDougall. His program will absolutely prevent heart disease.
Dr. Neal Barnard and Dr. Dean Ornish are two other doctors who push a similar diet to Dr. McDougall's.
Posted by gs | October 6, 2009 11:03 PM